Fibroblast growth factor 21 and prognosis of patients with cardiovascular disease: A meta-analysis.

ABSTRACT:

Background

The role of fibroblast growth factor 21 (FGF21) in predicting the long-term prognosis of patients with cardiovascular disease (CVD) remains unknown.

Methods

A comprehensive search in PubMed, Embase, and the Cochrane Library was performed to identify studies reporting the association between FGF21 and prognosis among patients with CVD. A meta-analysis was performed, with patients stratified by coronary artery disease (CAD) or heart failure (HF). The endpoint of CAD or HF was major adverse cardiovascular events defined by each study and a composite of death or HF readmission, respectively. The I² method and linear regression test of funnel plot asymmetry were used to test heterogeneity (I² > 50% indicates substantial heterogeneity) and publicat

SUBMITTER: Yan B 

PROVIDER: S-EPMC10011636 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature