Diagnostic Accuracy of Portable, Handheld Point-of-Care Tests vs Laboratory-Based Bilirubin Quantification in Neonates: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Quantification of bilirubin in blood is essential for early diagnosis and timely treatment of neonatal hyperbilirubinemia. Handheld point-of-care (POC) devices may overcome the current issues with conventional laboratory-based bilirubin (LBB) quantification.

Objective

To systematically evaluate the reported diagnostic accuracy of POC devices compared with LBB quantification.

Data sources

A systematic literature search was conducted in 6 electronic databases (Ovid MEDLINE, Embase, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, CINAHL, and Google Scholar) up to December 5, 2022.

Study selection

Studies were included in this systematic review and meta-analysis if they had a prospective cohort, retrospective cohort, or cr

SUBMITTER: Westenberg LEH 

PROVIDER: S-EPMC10012043 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature