Cardiovascular events and risk in patients with systemic lupus erythematosus: Systematic literature review and meta-analysis.

ABSTRACT:

Background

Systemic lupus erythematosus (SLE) is an autoimmune disease that typically affects women aged 16-55 years. Cardiovascular disease (CVD) is a well-recognized complication of SLE. This systematic literature review and meta-analysis evaluated the relative risk (RR; compared with non-SLE controls), absolute risk (AR; as incidence proportion, n/N), and incidence rate (IR) of CVD events (including stroke, myocardial infarction [MI], and CVD [composite or undefined]) in adult patients with SLE. The RR of CV risk factors (including hypertension, diabetes, and metabolic syndrome [MetS]) was also examined.

Methods

PubMed and Embase were searched on September 10, 2020. Observational studies published between January 2010 and September 2020 that reported RR, AR, and/or IR of

SUBMITTER: Bello N 

PROVIDER: S-EPMC10012401 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature