Age Moderates the Effect of Obesity on Mortality Risk in Critically Ill Patients With COVID-19: A Nationwide Observational Cohort Study.

ABSTRACT:

Objectives

A high body mass index (BMI) is associated with an unfavorable disease course in COVID-19, but not among those who require admission to the ICU. This has not been examined across different age groups. We examined whether age modifies the association between BMI and mortality among critically ill COVID-19 patients.

Design

An observational cohort study.

Setting

A nationwide registry analysis of critically ill patients with COVID-19 registered in the National Intensive Care Evaluation registry.

Patients

We included 15,701 critically ill patients with COVID-19 (10,768 males [68.6%] with median [interquartile range] age 64 yr [55-71 yr]), of whom 1,402 (8.9%) patients were less than 45 years.

Interventions

None.

Measurements and main results

SUBMITTER: den Uil CA 

PROVIDER: S-EPMC10012838 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature