Antenatal azithromycin to prevent preterm birth in pregnant women with vaginal cerclage: A randomized clinical trial.

ABSTRACT:

Objective

To assess whether antenatal azithromycin given to pregnant women with vaginal cerclage can reduce preterm birth or not.

Materials and methods

We randomized 50 pregnant ladies who underwent cerclage at Ain Shams University Maternity Hospital in group A (receiving 500 mg Azithromycin oral tablets (Zithrokan^®, Hikma, Egypt) one tablet orally twice daily for three days in 3 courses at 14^th, 24^th and 32^nd week, plus usual antenatal care) and an identical group B (receiving usual antenatal care). Our primary outcome was gestational age at delivery, and secondary outcomes were birthweight, mode of delivery, and maternal, and perinatal complications. This study was registered on ClinicalTrials.gov with number: NCT04278937.

Res

SUBMITTER: Ahmed RHM 

PROVIDER: S-EPMC10013083 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature