Does Long-Term Post-Bariatric Weight Change Differ Across Antidepressants?

ABSTRACT: We sought to evaluate whether weight change up to 5 years after bariatric surgery differed by antidepressant class taken before surgery.

Background

Bariatric surgery induces significant weight loss, but outcomes are highly variable. The specific type of antidepressant used prior to surgery may be an important factor in long-term weight loss.

Methods

This retrospective cohort study from 2000 to 2016 compared the 5-year weight loss of 556 Veterans who were taking antidepressant monotherapy (bupropion, selective serotonin reuptake inhibitors [SSRIs], or serotonin-norepinephrine reuptake inhibitors [SNRIs]) before bariatric surgery (229 sleeve gastrectomy and 327 Roux-en-Y gastric bypass) versus 556 matched nonsurgical controls.

Results

Patients taking bupropion before sle

SUBMITTER: Arterburn DE 

PROVIDER: S-EPMC10013150 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature