Biocompatible Short-Peptides Fibrin Co-assembled Hydrogels.

ABSTRACT: Fibrin hydrogels made by self-assembly of fibrinogen obtained from human plasma have shown excellent biocompatible and biodegradable properties and are widely used in regenerative medicine. The fibrinogen self-assembly process can be triggered under physiological conditions by the action of thrombin, allowing the injection of pregel mixtures that have been used as cell carriers, wound-healing systems, and bio-adhesives. However, access to fibrinogen from human plasma is expensive and fibrin gels have limited mechanical properties, which make them unsuitable for certain applications. One solution to these problems is to obtain composite gels made of fibrin and other polymeric compounds that improve their mechanical properties and usage. Herein, we prepared composite hydrogels made by the se

SUBMITTER: Gila-Vilchez C 

PROVIDER: S-EPMC10013376 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature