A phylogenetic study of dengue virus in urban Vietnam shows long-term persistence of endemic strains.

ABSTRACT: Dengue virus (DENV) causes repeated outbreaks of disease in endemic areas, with patterns of local transmission strongly influenced by seasonality, importation via human movement, immunity, and vector control efforts. An understanding of how each of these interacts to enable endemic transmission (continual circulation of local virus strains) is largely unknown. There are times of the year when no cases are reported, often for extended periods of time, perhaps wrongly implying the successful eradication of a local strain from that area. Individuals who presented at a clinic or hospital in four communes in Nha Trang, Vietnam, were initially tested for DENV antigen presence. Enrolled positive individuals then had their corresponding household members invited to participate, and those who enrol

SUBMITTER: Ashall J 

PROVIDER: S-EPMC10013730 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature