Serum Irisin level is associated with fall risk, muscle strength, and cortical porosity in postmenopausal women.

ABSTRACT:

Background

Irisin plays a role in bone-muscle crosstalk, but the relationship between the serum irisin level and bone microarchitecture remains unknown.

Objective

This study aimed to investigate the relationships between serum irisin level and fall risk, muscle strength, bone mineral density (BMD), and bone microarchitecture among Chinese postmenopausal women.

Methods

In all 138 postmenopausal women, handgrip strength, short physical performance battery (SPPB), and the timed up-and-go test were performed to evaluate muscle strength, physical performance, and fall risk, respectively. The serum irisin was measured. High-resolution peripheral quantitative computed tomography (HR-pQCT) was performed to acquire volumetric BMD and bone microarchitecture. Bivariate analysis

SUBMITTER: Liang H 

PROVIDER: S-EPMC10013910 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature