Self-reported quality of life in symptomatic and asymptomatic women with X-linked adrenoleukodystrophy.

ABSTRACT:

Background

Up to 80% of women with X-linked adrenoleukodystrophy (X-ALD) develop symptoms of myelopathy and peripheral neuropathy during their lifetime. The study's objective was to compare symptomatic versus asymptomatic women with X-ALD regarding their physical and mental well-being and quality of life.

Methods

Data were obtained from a prospective, international, cross-sectional cohort study of women with X-ALD recruited both clinically and population based. Symptoms, quality of life, and physical and mental co-morbidities were assessed by questionnaires. Women were considered symptomatic if they reported any sign of myelopathy or peripheral neuropathy. Group differences between symptomatic versus asymptomatic women and between age groups were examined using χ²

SUBMITTER: Schafer L 

PROVIDER: S-EPMC10013936 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature