One-Pot Protolignin Extraction by Targeted Unlocking Lignin-Carbohydrate Esters via Nucleophilic Addition-Elimination Strategy.

ABSTRACT: Protolignin extraction can facilitate structure elucidation and valorization of lignin in biorefinery, but is rather challenging due to the complex chemical bonds present. Here, we developed the in situ generated NH₃-reline (IGNR) system to realize one-pot protolignin extraction from lignocellulose. In the IGNR system, reline consisting of choline chloride and urea acted as both a solvent and a nucleophile generator, and the nucleophilic addition-elimination mechanism was verified by model compound studies. The in situ generated NH₃ could precisely cleave the lignin-carbohydrate esters in lignocellulose with a near-quantitative retention of carbohydrates. The extracted IGNR-Protolignin exhibited native lignin substructure with high molecular weight and high β-O-4' con

SUBMITTER: Lou Y 

PROVIDER: S-EPMC10013968 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature