Disorder of consciousness: Structural integrity of brain networks for the clinical assessment.

ABSTRACT:

Aim

When studying brain networks in patients with Disorders of Consciousness (DoC), it is important to evaluate the structural integrity of networks in addition to their functional activity. Here, we investigated whether structural MRI, together with clinical variables, can be useful for diagnostic purposes and whether a quantitative analysis is feasible in a group of chronic DoC patients.

Methods

We studied 109 chronic patients with DoC and emerged from DoC with structural MRI: 65 in vegetative state/unresponsive wakefulness state (VS/UWS), 34 in minimally conscious state (MCS), and 10 with severe disability. MRI data were analyzed through qualitative and quantitative approaches.

Results

The qualitative MRI analysis outperformed the quantitative one, which resulted t

SUBMITTER: Medina Carrion JP 

PROVIDER: S-EPMC10014003 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature