Motor processivity and speed determine structure and dynamics of microtubule-motor assemblies.

ABSTRACT: Active matter systems can generate highly ordered structures, avoiding equilibrium through the consumption of energy by individual constituents. How the microscopic parameters that characterize the active agents are translated to the observed mesoscopic properties of the assembly has remained an open question. These active systems are prevalent in living matter; for example, in cells, the cytoskeleton is organized into structures such as the mitotic spindle through the coordinated activity of many motor proteins walking along microtubules. Here, we investigate how the microscopic motor-microtubule interactions affect the coherent structures formed in a reconstituted motor-microtubule system. This question is of deeper evolutionary significance as we suspect motor and microtubule type contr

SUBMITTER: Banks RA 

PROVIDER: S-EPMC10014072 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature