The association between arterial stiffness and cancer occurrence: Data from Kailuan cohort study.

ABSTRACT:

Background

This study aimed to investigate whether increased arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV) is associated with cancer.

Materials and methods

A total of 45,627 Chinese adults underwent a baPWV examination. The participants were followed up from 1st January 2012 to 31st December 2018. Cox proportional hazards model was used to assess the association between the baPWV values and cancer.

Results

During a total follow-up duration of 172,775.69 person-years, there were 553 new cases of cancer. The subjects in the highest baPWV group showed an increased risk of cancer when compared with the lowest baPWV group as confirmed by multivariate-adjusted hazard ratios (HR = 1.51, 95% CI = 1.14∼2.00) in the entire cohort. Compared with part

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC10014543 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature