TMS-evoked EEG potentials demonstrate altered cortical excitability in migraine with aura.

ABSTRACT: Migraine is associated with altered sensory processing, that may be evident as changes in cortical responsivity due to altered excitability, especially in migraine with aura. Cortical excitability can be directly assessed by combining transcranial magnetic stimulation with electroencephalography (TMS-EEG). We measured TMS evoked potential (TEP) amplitude and response consistency as these measures have been linked to cortical excitability but were not yet reported in migraine.We recorded 64-channel EEG during single-pulse TMS on the vertex interictally in 10 people with migraine with aura and 10 healthy controls matched for age, sex and resting motor threshold. On average 160 pulses around resting motor threshold were delivered through a circular coil in clockwise and counterclockwise direc

SUBMITTER: Helling RM 

PROVIDER: S-EPMC10014725 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature