Tuberculosis remains a major burden in systemic lupus erythematosus patients in Durban, South Africa.

ABSTRACT:

Objective

Infections are common in systemic lupus erythematosus (SLE), with tuberculosis (TB) being important in an endemic environment. We studied the prevalence and spectrum of TB in SLE in Durban, South Africa.

Methods

A medical records review of SLE patients seen over 13-year period, and the demographic data, clinical manifestations, laboratory findings, treatment and outcome were noted.

Results

There were 512 SLE patients and 72 (14.1%) had TB. Thirty (41.7%) had pulmonary TB (PTB) and 42 (58.3%) had extra-pulmonary TB (EPTB). The prevalence of TB among the different ethnic groups was 36/282 (12.8%) for Indian people, 29/184 (15.8%) Black African people, 7/26 (26.9%) admixed African people and none among the 18 White people. Comparison of the 72 SLE-TB patients w

SUBMITTER: Al-Arbi KMS 

PROVIDER: S-EPMC10014752 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature