Central-line-associated bloodstream infections and central-line-associated non-CLABSI complications among pediatric oncology patients.

ABSTRACT:

Objective

To assess central venous catheter (CVC) harm in pediatric oncology patients, we explored risks for central-line-associated bloodstream infections (CLABSIs) and central-line-associated non-CLABSI complications (CLANCs).

Design

Retrospective cohort study.

Setting

Midwestern US pediatric oncology program.

Patients

The study cohort comprised 592 pediatric oncology patients seen between 2006 and 2016.

Methods

CLABSIs were defined according to Centers for Disease Control and Prevention (CDC)/National Health Safety Network (NHSN) definitions. CLANCs were classified using a novel definition requiring CVC removal. Patient-level and central-line-level risks were calculated using a negative binomial model to adjust for correlations between total events an

SUBMITTER: Kelada AS 

PROVIDER: S-EPMC10015264 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature