Sense of meaning and purpose in life and risk of incident dementia: New data and meta-analysis.

ABSTRACT:

Purpose

A greater sense of meaning and purpose in life is associated with lower dementia risk. The present research examines meaning and incident dementia in the largest sample to date, the UK Biobank, and combines the findings with the published literature on meaning/purpose and dementia risk in a meta-analysis.

Method

Participants from the UK Biobank reported on their meaning in life in the 2016/2017 mental health assessment (N=153,445). All-cause and cause-specific dementia were derived from hospital and death records through November 2021. Cox regression was used to test the association between meaning in life and risk of incident dementia. Results from the UK Biobank were combined with published studies identified through a systematic literature review in a random-effec

SUBMITTER: Sutin DAR 

PROVIDER: S-EPMC10015423 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature