Polishing De Novo Nanopore Assemblies of Bacteria and Eukaryotes With FMLRC2.
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ABSTRACT:
SUBMITTER: Mak QXC
PROVIDER: S-EPMC10015616 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Publications
Polishing De Novo Nanopore Assemblies of Bacteria and Eukaryotes With FMLRC2.
Mak Q X Charles QXC Wick Ryan R RR Holt James Matthew JM Wang Jeremy R JR
Molecular biology and evolution 20230301 3
As the accuracy and throughput of nanopore sequencing improve, it is increasingly common to perform long-read first de novo genome assemblies followed by polishing with accurate short reads. We briefly introduce FMLRC2, the successor to the original FM-index Long Read Corrector (FMLRC), and illustrate its performance as a fast and accurate de novo assembly polisher for both bacterial and eukaryotic genomes. ...[more]
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