Polishing De Novo Nanopore Assemblies of Bacteria and Eukaryotes With FMLRC2.

ABSTRACT: As the accuracy and throughput of nanopore sequencing improve, it is increasingly common to perform long-read first de novo genome assemblies followed by polishing with accurate short reads. We briefly introduce FMLRC2, the successor to the original FM-index Long Read Corrector (FMLRC), and illustrate its performance as a fast and accurate de novo assembly polisher for both bacterial and eukaryotic genomes.

SUBMITTER: Mak QXC 

PROVIDER: S-EPMC10015616 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature