Air pollution, depressive and anxiety disorders, and brain effects: A systematic review.

ABSTRACT: Accumulating data suggest that air pollution increases the risk of internalizing psychopathology, including anxiety and depressive disorders. Moreover, the link between air pollution and poor mental health may relate to neurostructural and neurofunctional changes. We systematically reviewed the MEDLINE database in September 2021 for original articles reporting effects of air pollution on 1) internalizing symptoms and behaviors (anxiety or depression) and 2) frontolimbic brain regions (i.e., hippocampus, amygdala, prefrontal cortex). One hundred and eleven articles on mental health (76% human, 24% animals) and 92 on brain structure and function (11% human, 86% animals) were identified. For literature search 1, the most common pollutants examined were PM_2.5 (64.9%), NO₂

SUBMITTER: Zundel CG 

PROVIDER: S-EPMC10015654 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature