Stability in gene expression and body-plan development leads to evolutionary conservation.

ABSTRACT:

Background

Phenotypic evolution is mainly explained by selection for phenotypic variation arising from factors including mutation and environmental noise. Recent theoretical and experimental studies have suggested that phenotypes with greater developmental stability tend to have a constant phenotype and gene expression level within a particular genetic and environmental condition, and this positively correlates with stronger evolutionary conservation, even after the accumulation of genetic changes. This could reflect a novel mechanism that contributes to evolutionary conservation; however, it remains unclear whether developmental stability is the cause, or whether at least it contributes to their evolutionary conservation. Here, using Japanese medaka lines, we tested experimentally

SUBMITTER: Uchida Y 

PROVIDER: S-EPMC10015717 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature