Critical windows of exposure to air pollution and gestational diabetes: assessing effect modification by maternal pre-existing conditions and environmental factors.

ABSTRACT:

Background

Ambient air pollution has been associated with gestational diabetes (GD), but critical windows of exposure and whether maternal pre-existing conditions and other environmental factors modify the associations remains inconclusive.

Methods

We conducted a retrospective cohort study of all singleton live birth that occurred between April 1^st 2006 and March 31^st 2018 in Ontario, Canada. Ambient air pollution data (i.e., fine particulate matter with a diameter ≤ 2.5 μm (PM_2.5), nitrogen dioxide (NO₂) and ozone (O₃)) were assigned to the study population in spatial resolution of approximately 1 km × 1 km. The Normalized Difference Vegetation Index (NDVI) and the Green View Index (GVI) were also used to characterize r

SUBMITTER: Miron-Celis M 

PROVIDER: S-EPMC10015960 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature