Oral microbiome variations related to ageing: possible implications beyond oral health.

ABSTRACT: The global population is getting older due to a combination of longer life expectancy and declining birth rates. Growing evidence suggests that the oral microbiota composition and distribution may have a profound effect on how well we age. The purpose of this study was to investigate age-related oral microbiome variations of supragingival plaque and buccal mucosa samples in the general population in Latvia. Our results indicated significant difference between supragingival plaque bacterial profiles of three age groups (20-40; 40-60; 60 + years). Within supragingival plaque samples, age group 20-40 showed the highest bacterial diversity with a decline during the 40-60 age period and uprise again after the age of 60. Among other differences, the important oral commensal Neisseria had decline

SUBMITTER: Kazarina A 

PROVIDER: S-EPMC10016173 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature