Mechanistic studies of the palladium-catalyzed S,O-ligand promoted C-H olefination of aromatic compounds.

ABSTRACT: Pd-catalyzed C-H functionalization reactions of non-directed substrates have recently emerged as an attractive alternative to the use of directing groups. Key to the success of these transformations has been the discovery of new ligands capable of increasing both the reactivity of the inert C-H bond and the selectivity of the process. Among them, a new type of S,O-ligand has been shown to be highly efficient in promoting a variety of Pd-catalyzed C-H olefination reactions of non-directed arenes. Despite the success of this type of S,O-ligand, its role in the C-H functionalization processes is unknown. Herein, we describe a detailed mechanistic study focused on elucidating the role of the S,O-ligand in the Pd-catalyzed C-H olefination of non-directed arenes. For this purpose, several mechan

SUBMITTER: Naksomboon K 

PROVIDER: S-EPMC10016329 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature