Cumulative Environmental Risk in Early Life: Associations With Schizotypy in Childhood.

ABSTRACT:

Background and hypothesis

Psychotic disorders are associated with a growing number of recognized environmental exposures. Cumulative exposure to multiple environmental risk factors in childhood may contribute to the development of different patterns of schizotypy evident in early life. Hypotheses were that distinct profiles of schizotypy would have differential associations with a cumulative score of environmental risk factors.

Study design

We prospectively examined the relationship between 19 environmental exposures (which had demonstrated replicated associations with psychosis) measured from the prenatal period through to age 11 years, and 3 profiles of schizotypy in children (mean age = 11.9 years, n = 20 599) that have been established in population data from the New Sou

SUBMITTER: O'Hare K 

PROVIDER: S-EPMC10016419 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature