Association of lymphopenia and RDW elevation with risk of mortality in acute aortic dissection.

ABSTRACT:

Objective

The study aimed to investigate whether lymphopenia and red blood cell distribution width (RDW) elevation are associated with an increased risk of mortality in acute aortic dissection (AAD).

Methods

This multicenter retrospective cohort study enrolled patients diagnosed with AAD by aortic computed tomographic angiography (CTA) from 2010 to 2021 in five teaching hospitals in central-western China. Cox proportional hazards regression and Kaplan-Meier curves were used in univariable and multivariable models. Clinical outcomes were defined as all-cause in-hospital mortality, while associations were evaluated between lymphopenia, accompanied by an elevated RDW, and risk of mortality.

Results

Of 1903 participants, the median age was 53 (interquartile range [IQR], 4

SUBMITTER: Yu D 

PROVIDER: S-EPMC10016706 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature