Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages.

ABSTRACT: Following a stroke in regions of the brain responsible for motor activity, patients can lose their ability to control parts of their body. Over time, some patients recover almost completely, while others barely recover at all. It is known that lesion volume, initial motor impairment and cortico-spinal tract asymmetry significantly impact motor changes over time. Recent work suggested that disabilities arise not only from focal structural changes but also from widespread alterations in inter-regional connectivity. Models that consider damage to the entire network instead of only local structural alterations lead to a more accurate prediction of patients' recovery. However, assessing white matter connections in stroke patients is challenging and time-consuming. Here, we evaluated in a data s

SUBMITTER: Rivier C 

PROVIDER: S-EPMC10016810 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature