Cardiac Troponin, Cognitive Function, and Dementia: A Systematic Review.

ABSTRACT: Elevated cardiac troponin, a biomarker of myocardial injury, has been found in individuals with brain damage and lower cognitive function. We conducted a systematic review to examine the association of troponin with cognitive function, incidence of dementia and dementia-related outcomes. PubMed, Web of Science and EMBASE were searched from inception to August 2022. Inclusion criteria were: (i) population-based cohort studies; (ii) troponin measured as determinant; and (iii) cognitive function in any metric or diagnosis of any type of dementia or dementia-related measures as outcomes. Fourteen studies were identified and included, with a combined total of 38,286 participants. Of these studies, four examined dementia-related outcomes, eight studies examined cognitive function, and two studie

SUBMITTER: Zonneveld MH 

PROVIDER: S-EPMC10017151 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature