A new integrative approach to assess aortic stenosis burden and predict objective functional improvement after TAVR.

ABSTRACT:

Background

A non-negligible rate of patients undergoing transcatheter aortic valve replacement (TAVR) do not report symptomatic improvement or even die in the short-midterm. We sought to assess the degree of objective functional recovery after TAVR and its prognostic implications and to develop a predictive model.

Methods

In a cohort of patients undergoing TAVR, a prospective evaluation of clinical, anatomical, and physiological parameters was conducted before and after the procedure. These parameters were derived from echocardiography, non-invasive analysis of arterial pulse waves, and cardiac tomography. Objective functional improvement 6 months after TAVR was assessed using a 6-min walk test and nitro-terminal pro-brain natriuretic peptide (NT-proBNP) levels. The derived

SUBMITTER: de la Torre Hernandez JM 

PROVIDER: S-EPMC10017439 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature