Identifying optimal candidates for post-TIPS patients with HCC undergoing TACE: a multicenter observational study.

ABSTRACT:

Objective

To develop a prognostic model for post-transjugular intrahepatic portosystemic shunt (TIPS) patients with hepatocellular carcinoma (HCC) beyond the Milan criteria treated by transarterial chemoembolization (TACE).

Design

Between January 2013 and January 2020, 512 patients with HCC beyond the Milan criteria who underwent TACE after TIPS were retrospectively recruited from 15 tertiary centers. Patients were randomly sorted into a training set (n = 382) and a validation set (n = 130). Medical data and overall survival were assessed. A prediction model was developed using multivariate Cox regression analyses. Predictive performance and discrimination were evaluated and compared with other prognostic models.

Results

Vascular invasion, log₁₀(AFP), 1/cre

SUBMITTER: Fan W 

PROVIDER: S-EPMC10017639 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature