Effect of fecal microbiota transplantation in children with autism spectrum disorder: A systematic review.

ABSTRACT:

Background

Fecal microbiota transplantation (FMT) may be helpful in the treatment of autism spectrum disorder (ASD) as rebalancing the gut microbiome has been shown to potentially improve behavioral symptoms in children with ASD.

Methods

This systematic review was conducted to assess the effect of FMT for children with ASD. The Embase, PubMed, Web of Science, and Cochrane Library databases were searched for articles published from inception to October 6, 2022. Two reviewers independently screened the identified records and undertook data extraction.

Results

The search identified a total of five studies: two prospective open-label studies, two retrospective observational studies, and a case report; however, no randomized controlled trial was identified. All five studie

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10017995 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature