Design of a data set of qPCR primers for the early region of Human Papillomavirus oncogenic types 16 and 18.

ABSTRACT: High-Risk Human Papillomavirus (HR-HPV) types 16 and 18 are estimated to be responsible for 72.4% of all HPV-related cancers worldwide in both men and women, including cervical, anal, penile, vulval, vaginal and head and neck cancers [1]. Important efforts worldwide have devoted to the study of these genotypes, throughout epidemiology and basic science approaches. Of particular interest are the genes from the early region (E), coding non-structural proteins. Early genes E1 and E2 products are involved in replication and transcription regulation, while E6 and E7 proteins are recognised for their oncogenic potential. In this data report, we described a set of primers based on reference sequences from HPV16 and HPV18 designed to cover the early region of these oncogenic genotypes. The design

SUBMITTER: Kantun-Moreno N 

PROVIDER: S-EPMC10018045 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature