Thoracic motion-compensated cone-beam computed tomography in under 20 seconds on a fast-rotating linac: A simulation study.

ABSTRACT:

Background

Rapid kV cone-beam computed tomography (CBCT) scans are achievable in under 20 s on select linear accelerator systems to generate volumetric images in three dimensions (3D). Daily pre-treatment four-dimensional CBCT (4DCBCT) is recommended in image-guided lung radiotherapy to mitigate the detrimental effects of respiratory motion on treatment quality.

Purpose

To demonstrate the potential for thoracic 4DCBCT reconstruction using projection data that was simulated using a clinical rapid 3DCBCT acquisition protocol.

Methods

We simulated conventional (1320 projections over 4 min) and rapid (491 projections over 16.6 s) CBCT acquisitions using 4D computed tomography (CT) volumes of 14 lung cancer patients. Conventional acquisition data were reconstructed using t

SUBMITTER: Blake SJ 

PROVIDER: S-EPMC10018653 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature