The level of serum albumin is associated with renal prognosis and renal function decline in patients with chronic kidney disease.

ABSTRACT:

Objective

The study's purpose is to explore the link of serum albumin on renal progression in patients with chronic kidney disease (CKD).

Methods

This study was a secondary analysis of a prospective cohort study in which a total of 954 participants were non-selectively and consecutively collected from the research of CKD-ROUTE in Japan between November 2010 and December 2011. We evaluated the association between baseline ALB and renal prognosis (initiation of dialysis or 50% decline in eGFR from baseline) and renal function decline (annual eGFR decline) using the Cox proportional-hazards and linear regression models, respectively. We performed a number of sensitivity analyses to ensure the validity of the results. In addition, we performed subgroup analyses.

Results

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SUBMITTER: Cheng T 

PROVIDER: S-EPMC10018824 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature