Value of lymph node ratio as a prognostic factor of recurrence in medullary thyroid cancer.

ABSTRACT:

Background and objectives

The purpose of this study is to evaluate the relationship between lymph node status (the number of resected lymph nodes; the number of metastatic lymph nodes, LNM, and lymph node ratio, LNR) and biochemical recurrence, disease-free survival (DFS), as well as overall survival (OS) in medullary thyroid carcinoma (MTC).

Methods

This study enrolled MTC patients at Tianjin Medical University Cancer Institute and Hospital between 2011 and 2019. We used Logistic regression analysis, Cox regression models and Kaplan-Meier test to identify risk factors influencing biochemical recurrence, DFS, and OS.

Results

We identified 160 patients who satisfied the inclusion criteria from 2011 to 2019. We used ROC analysis to define the cut-off value of LNR with 0

SUBMITTER: Hao W 

PROVIDER: S-EPMC10019331 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature