Future directions for medicinal chemistry in the field of oligonucleotide therapeutics.

ABSTRACT: In the last decade, the field of oligonucleotide therapeutics has matured, with the regulatory approval of several single-stranded and double-stranded RNA drugs. In this Perspective, I discuss enabling developments and likely future directions in the field from the perspective of oligonucleotide chemistry.

SUBMITTER: Hall J 

PROVIDER: S-EPMC10019366 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature