Association between prior tuberculosis disease and dysglycemia within an HIV-endemic, rural South African population.

ABSTRACT:

Objective

Tuberculosis (TB) may predispose individuals to the development of diabetes. Such a relationship could have an outsized impact in high-prevalence TB settings. However, few studies have explored this relationship in populations heavily burdened by diabetes and TB.

Methods

We analyzed data from a community-based population cohort that enrolled adults in rural South Africa. Individuals were considered to have prior TB if they self-reported a history of TB treatment. We fitted sex-specific logistic regression models, adjusted for potential clinical and demographic confounders, to estimate relationships between dysglycemia (HBA1c ≥6.5%) and prior TB. Propensity score-matched cohorts accounted for the differential age distributions between comparator groups. We examined

SUBMITTER: Castle AC 

PROVIDER: S-EPMC10019670 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature