Association between short-term exposure to environmental air pollution and atopic dermatitis flare in patients treated with dupilumab.

ABSTRACT:

Background

The magnitude of short/medium-term air pollution exposure on atopic dermatitis (AD) flare has not been fully investigated. The aim of the study was to investigate the association of short/medium-term exposure to airborne pollution on AD flares in patients treated with dupilumab.

Methods

Observational case-crossover study. Patients with moderate-to-severe AD under treatment with dupilumab were included. The exposure of interest was the mean concentrations of coarse and fine particulate matter (PM₁₀, PM_2.5), nitrogen dioxide, and oxides (NO₂, NO_x). Different intervals were considered at 1 to 60 days before the AD flare and control visit, defined as the visit with the highest Eczema Area and Severity Index scores >8

SUBMITTER: Bellinato F 

PROVIDER: S-EPMC10020116 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature