Methods and system for recording human physiological signals from implantable leads during spinal cord stimulation.

ABSTRACT:

Objectives

This article presents a method-including hardware configuration, sampling rate, filtering settings, and other data analysis techniques-to measure evoked compound action potentials (ECAPs) during spinal cord stimulation (SCS) in humans with externalized percutaneous electrodes. The goal is to provide a robust and standardized protocol for measuring ECAPs on the non-stimulation contacts and to demonstrate how measured signals depend on hardware and processing decisions.

Methods

Two participants were implanted with percutaneous leads for the treatment of chronic pain with externalized leads during a trial period for stimulation and recording. The leads were connected to a Neuralynx ATLAS system allowing us to simultaneously stimulate and record through selected elect

SUBMITTER: Ramadan A 

PROVIDER: S-EPMC10020336 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature