Relationship between risk factors for impaired bone health and HR-pQCT in young adults with type 1 diabetes.

ABSTRACT:

Objective

In type 1 diabetes, risk factors associated with impaired bone health contribute to increased risk of fracture. The aim of this study was to (1): compare the high-resolution peripheral quantitative computed tomography (HR-pQCT) parameters of young adults with type 1 diabetes with those of healthy controls (2), identify sex differences, and (3) evaluate the association between diabetes and bone health risk factors, with HR-pQCT.

Methods

This is a cross-sectional study in young Canadian adults with childhood onset type 1 diabetes. Z-scores were generated for HR-pQCT parameters using a large healthy control database. Diet, physical activity, BMI, hemoglobin A1C (A1C) and bone health measures were evaluated, and associations were analyzed using multivariate regression

SUBMITTER: Sochett EB 

PROVIDER: S-EPMC10020337 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature