External validation and improvement of the scoring system for predicting the prognosis in hepatocellular carcinoma after interventional therapy.

ABSTRACT:

Background

Currently, locoregional therapies, such as transarterial chemoembolization (TACE) and ablation, play an important role in the treatment of Hepatocellular carcinoma (HCC). However, an easy-to-use scoring system that predicts recurrence to guide individualized management of HCC with varying risks of recurrence remains an unmet need.

Methods

A total of 483 eligible HCC patients treated by TACE combined with ablation from January 1, 2017, to December 31, 2019, were included in the temporal external validation cohort and then used to explore possibilities for refinement of the original scoring system. We investigated the prognostic value of baseline variables on recurrence-free survival (RFS) using a Cox model and developed the easily applicable YA score. The performan

SUBMITTER: Qiao W 

PROVIDER: S-EPMC10020369 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature