Comparison of Four Clinical Prognostic Scores in Patients with Advanced Gastric and Esophageal Cancer.

ABSTRACT:

Background

Prognostic scores that can identify patients at risk for early death are needed to aid treatment decision-making and patient selection for clinical trials. We compared the accuracy of four scores to predict early death (within 90 days) and overall survival (OS) in patients with metastatic gastric and esophageal (GE) cancer.

Methods

Advanced GE cancer patients receiving first-line systemic therapy were included. Prognostic risks were calculated using: Royal Marsden Hospital (RMH), MD Anderson Cancer Centre (MDACC), Gustave Roussy Immune (GRIm-Score), and MD Anderson Immune Checkpoint Inhibitor (MDA-ICI) scores. Overall survival (OS) was estimated using the Kaplan-Meier method. Cox proportional hazards models were used to analyze associations between prognostic scor

SUBMITTER: Ma LX 

PROVIDER: S-EPMC10020804 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature