Resorc[4]arene-Modified Gold-Decorated Magnetic Nanoparticles for Immunosensor Development.

ABSTRACT: In recent years, several efforts have been made to develop selective, sensitive, fast response, and miniaturized immunosensors with improved performance for the monitoring and screening of analytes in several matrices, significantly expanding the use of this technology in a broad range of applications. However, one of the main technical challenges in developing immunosensors is overcoming the complexity of binding antibodies (Abs) to the sensor surface. Most immobilizing approaches lead to a random orientation of Abs, resulting in lower binding site density and immunoaffinity. In this context, supramolecular chemistry has emerged as a suitable surface modification tool to achieve the preorganization of artificial receptors and to improve the functional properties of self-assembled monolaye

SUBMITTER: Calcaterra A 

PROVIDER: S-EPMC10020960 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature