Target product profiles for novel medicines to prevent and treat preeclampsia: An expert consensus.

ABSTRACT:

Background

Preeclampsia and eclampsia are a leading cause of global maternal and newborn mortality. Currently, there are few effective medicines that can prevent or treat preeclampsia. Target Product Profiles (TPPs) are important tools for driving new product development by specifying upfront the characteristics that new products should take. Considering the lack of investment and innovation around new medicines for obstetric conditions, we aimed to develop two new TPPs for medicines to prevent and treat preeclampsia.

Methods and findings

We used a multi-methods approach comprised of a literature review, stakeholder interviews, online survey, and public consultation. Following an initial literature review, diverse stakeholders (clinical practice, research, academia, internat

SUBMITTER: Mcdougall AR 

PROVIDER: S-EPMC10021561 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature