Estimates of the cost to build a stand-alone environmental surveillance system for typhoid in low- and middle-income countries.

ABSTRACT: The typhoid conjugate vaccine is a safe and effective method for preventing Salmonella enterica serovar Typhi (typhoid) and the WHO's guidance supports its use in locations with ongoing transmission. However, many countries lack a robust clinical surveillance system, making it challenging to determine where to use the vaccine. Environmental surveillance is one alternative approach to identify ongoing transmission, but the cost to implement such a strategy is previously unknown. This paper estimated the cost of setting up and operating an environmental surveillance program for thirteen protocols that are in development, including thirteen cost components and twenty-seven pieces of equipment. Unit costs were obtained from research labs involved in protocol development and equipment informati

SUBMITTER: Hagedorn B 

PROVIDER: S-EPMC10021573 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature