Potential implementation strategies, acceptability, and feasibility of new and repurposed TB vaccines.

ABSTRACT: Recently, two Phase 2B tuberculosis vaccine trials reported positive efficacy results in adolescents and adults. However, experience in vaccinating these age groups is limited. We identified potential implementation strategies for the M72/AS01E vaccination and BCG-revaccination-like candidates and explored their acceptability and feasibility. We conducted in-depth semi-structured interviews among key decision makers to identify implementation strategies and target groups in South Africa, India, and China. Thematic and deductive analysis using a coding framework were used to identify themes across and within settings. In all three countries there was interest in novel TB vaccines, with school-attending adolescents named as a likely target group. In China and India, older people were also id

SUBMITTER: Pelzer PT 

PROVIDER: S-EPMC10021736 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature