Yeast hydrolysate attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage in weaned piglets.

ABSTRACT:

Background

Intestinal inflammation is the main risk factor causing intestinal barrier dysfunction and lipopolysaccharide (LPS) can trigger inflammatory responses in various eukaryotic species. Yeast hydrolysate (YH) possesses multi-biological effects and is received remarkable attention as a functional ingredient for improving growth performance and promoting health in animals. However, there is still inconclusive on the protective effects of dietary YH supplementation on intestinal barrier of piglets. This study was conducted to investigate the attenuate effects of YH supplementation on inflammatory responses and intestinal barrier injury in piglets challenged with LPS.

Methods

Twenty-four piglets (with an average body weight of 7.42 ± 0.34 kg) weaned at 21 days of age were

SUBMITTER: Fu R 

PROVIDER: S-EPMC10021991 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature