Antibody responses to Sinopharm/BBIBP-CorV in pregnant mothers in Sri Lanka.

ABSTRACT:

Background

There are limited data regarding the safety and immunogenicity of the Sinopharm/BBIBP-CorV vaccine in pregnancy. Therefore, we sought to investigate the antibody responses and maternal and fetal adverse events following this vaccine in pregnant mothers in Sri Lanka.

Methods and findings

SARS-CoV-2 receptor binding domain (RBD) specific total antibodies and ACE2 blocking antibodies were measured by ELISA in pregnant mothers (n = 94) who received the vaccine in the first (n = 2), second (n = 57) and third (n = 33) trimester of pregnancy. Data regarding adverse events and fetal and maternal outcomes were obtained from the women once they delivered. No adverse maternal or fetal complications reported such as miscarriage, thrombotic events, hypertensive disorders, feta

SUBMITTER: Jeewandara C 

PROVIDER: S-EPMC10022122 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature