The global burden of Chikungunya fever among children: A systematic literature review and meta-analysis.

ABSTRACT: Chikungunya fever (CHIKF) is an arboviral illness that was first described in Tanzania (1952). In adults, the disease is characterised by debilitating arthralgia and arthritis that can persist for months, with severe illness including neurological complications observed in the elderly. However, the burden, distribution and clinical features of CHIKF in children are poorly described. We conducted a systematic literature review and meta-analysis to determine the epidemiology of CHIKF in children globally by describing its prevalence, geographical distribution, and clinical manifestations. We searched electronic databases for studies describing the epidemiology of CHIKF in children. We included peer-reviewed primary studies that reported laboratory confirmed CHIKF. We extracted information on

SUBMITTER: Nyamwaya DK 

PROVIDER: S-EPMC10022366 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature