Toxicity and assimilation of cellulosic copper nanoparticles require α-arrestins in S. cerevisiae.

ABSTRACT: The increased use of antimicrobial compounds such as copper into nanoparticles changes how living cells interact with these novel materials. The increased use of antimicrobial nanomaterials combats infectious disease and food spoilage. Fungal infections are particularly difficult to treat because of the few druggable targets, and Saccharomyces cerevisiae provides an insightful model organism to test these new materials. However, because of the novel characteristics of these materials, it is unclear how these materials interact with living cells and if resistance to copper-based nanomaterials could occur. Copper nanoparticles built on carboxymethylcellulose microfibril strands with copper (CMC-Cu) are a promising nanomaterial when imported into yeast cells and induce cell death. The α-arres

SUBMITTER: Nurmalasari NPD 

PROVIDER: S-EPMC10022662 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature